Introduction: Giardiasis is a human health concern worldwide, especially among schoolchildren.Giardia duodenalis genotypes A and B are infective to humans, but their zoonotic potential remains controversial.In Mexico, the most prevalent genotype is A, but B was also detected in southeastern Mexico.In Sinaloa state, northwestern Mexico, giardiasis is highly prevalent, but Giardia genotypes have been poorly studied.Methodology: This study aimed to investigate the distribution and clinical-epidemiological correlation of G.
duodenalis genotypes in schoolchildren and their families and pets in urban and rural areas of Sinaloa state, Mexico.Results: new belial model Among 395 schoolchildren (274 urban, 121 rural), 76 (49 urban, 27 rural) were infected with G.duodenalis.In total, 22 families (15 urban, 7 rural) of infected schoolchildren, consisting of 60 family members (41 urban, 19 rural) and 21 pet dogs (15 urban, 6 rural) were examined; 10 family members (5 urban, 5 rural) and 5 pet read more dogs (3 urban, 2 rural) of 10 families (6 urban, 4 rural) were infected.After PCR-RFLP analyses of vsp417 and gdh genes, genotype prevalence among infected urban schoolchildren was 79.
5% AI, 12.8% AII, and 7.7% mixed AI+B.However, only AI genotype was found in family members and pets.In the rural area, only the AI genotype was detected.
Genotypes were not correlated with clinical manifestations.Conclusions: This paper shows the presence of B genotype in northwestern Mexico for the first time.Detection of AI genotype in dogs suggested the possible role of dogs as the reservoir for human giardiasis in Sinaloa, Mexico.